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. 2015;53(5):276-8.
doi: 10.5114/reum.2015.55831. Epub 2015 Dec 8.

Multiple pulmonary rheumatoid nodules

Gokhan Sargin  1 , Taskin Senturk  1
Affiliations

Multiple pulmonary rheumatoid nodules

Gokhan Sargin et al. Reumatologia. 2015.

Abstract

We present a case of 45-year-old female patient with the diagnosis of seropositive rheumatoid arthritis, who was admitted to our rheumatology department with exacerbation of the disease. The patient's disease activity score (DAS 28) was 6.9. Physical examination revealed changes in the lung auscultation as a rough breathing sound at the middle and lower lobe of the right lung. Chest X-ray revealed multiple nodular densities in both lungs. Lung biopsy was performed for the diagnosis and revealed necrotizing granulomas with central fibrinoid necrosis surrounded by epithelioid cells. Such a histopathological picture is typical for rheumatoid nodules. Finally the patient was treated with rituximab, with significant improvement.

Keywords: pulmonary changes; rheumatoid arthritis; rheumatoid nodule.

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Figures

Fig. 1
Fig. 1
Increased irregular nodular density in the lower and mid right zone.
Fig. 2
Fig. 2
Radiographic appearance of rheumatoid nodules in different areas of lung.
See this image and copyright information in PMC

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