Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2005 Feb;61(2):148-50.
doi: 10.1016/S0377-1237(05)80011-5. Epub 2011 Jul 21.

Outbreak of Multi-drug Resistant Salmonella Typhi Enteric Fever in Mumbai Garrison

R N Misra  1 , K S Bawa  2 , S K Magu  3 , S Bhandari  4 , A Nagendra  5 , P K Menon  6
Affiliations

Outbreak of Multi-drug Resistant Salmonella Typhi Enteric Fever in Mumbai Garrison

R N Misra et al. Med J Armed Forces India. 2005 Feb.

Abstract

Background: There was an epidemic of enteric fever in Mumbai garrison during Nov-Dec 2000 with more than 150 cases admitted to a tertiary care service hospital.

Methods: All the cases presented with fever and some had splenomegaly, bradycardia, abdominal pain and diarrhoea. The epidemic was investigated by the station health organization (SHO) and the case and bacteriological study was carried out in pathology laboratory of the service hospital. The serological study was carried out at Armed Forces Medical College (AFMC), Pune and the Phage typing was carried out at Lady Harding Medical College, New Delhi.

Results: Blood cultures were positive in 92(63%) for Salmonella typhi and Widal test was positive in 83(55%). All strains were resistant to four primary drugs i.e. ampicillin, chloramphenicol, co-trimoxazole and tetracycline. All but two were treated successfully with ceftriaxone. The Salmonella typhi belonged to phage group E1 and biotype I.

Conclusion: Extensive epidemiological investigation of cases and water sources of cantonment area pointed to a common source of the epidemic i.e. the well near 'Gurudwara'.

Keywords: Enteric fever; Multi-drug resistant; Phage type; Salmonella typhi.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Kamat SA, Herzog C. Typhoid: Clinical picture in response to chloramphenicol: prospective study in Bombay,1972. Infection. 1977;5:85–91. - PubMed
    1. Agarwal SC. Chloramphenicol resistance of Salmonella typhi in India, 1956–61. Bull Wld Hlth Orgn. 1962;17:331–335. - PMC - PubMed
    1. Sridhar H, Macaden R, Laxmidevi ML, Bhat P. Chloramphenicol resistance of Salmonella typhi in Bangalore. Ind J Med Res. 1983;78:314–318. - PubMed
    1. Konemann EW, Allen SD, Janda WM, Schreckenbenger PC, Winn WC Jr, editors. Diagnostic Microbiology. 5th ed. Lippincott; Philadelphia: 1997. pp. 171–241.
    1. Stokes EJ, Ridgway GL, Wren MWD, editors. Clinical Microbiology Edward Arnold,Boston: 7th ed. 1993;251-252.

Uncited Reference

    1. Agarwal V, Bhatmne RB, Dhanvijaya AN, Jalgoankar PD, Pathak AK, Saoji AM. Antibiogram, phage types and biotype of Salmonella typhi isolated in Nagpur. India J Med Res. 1992;95:4–6. - PubMed
    1. Anand AC, Kataria VK, Singh W, Chatterjee SK. An epidemic ofmultidrug resistant enteric fever in Calcutta. JAPI. 1991;39:11.