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. 2016 Jul 12;24(1):9-10.
doi: 10.1016/j.cmet.2016.06.023.

Microbially Produced Acetate: A "Missing Link" in Understanding Obesity?

Chad M Trent  1 , Martin J Blaser  2
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Microbially Produced Acetate: A "Missing Link" in Understanding Obesity?

Chad M Trent et al. Cell Metab. .
Free article

Abstract

Numerous studies have connected the gut microbiome with diet-induced obesity; however, mechanistic explanations for the host-microbial interactions are needed. Perry et al. (2016) present studies suggesting that microbially produced acetate (MPA) increases post-prandial insulin release via a sequential and integrated gut, brain, and pancreatic signaling network promoting energy retention.

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