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. 2016 Aug;107(2):99-100.
doi: 10.5935/abc.20160101. Epub 2016 Jul 11.

Clinical Course After Cardioverter-Defibrillator Implantation: Chagasic Versus Ischemic Patients

[Article in English, Portuguese]
Francisca Tatiana Moreira Pereira  1 , Eduardo Arrais Rocha  1 , Marcelo de Paula Martins Monteiro  1 , Neiberg de Alcantara Lima  1 , Carlos Roberto Martins Rodrigues Sobrinho  1 , Roberto da Justa Pires Neto  2
Affiliations

Clinical Course After Cardioverter-Defibrillator Implantation: Chagasic Versus Ischemic Patients

[Article in English, Portuguese]
Francisca Tatiana Moreira Pereira et al. Arq Bras Cardiol. 2016 Aug.

Abstract

Background: The outcome of Chagas disease patients after receiving implantable cardioverter defibrillator (ICD) is still controversial.

Objective: To compare clinical outcomes after ICD implantation in patients with chronic Chagas cardiomyopathy (CCC) and ischemic heart disease (IHD).

Methods: Prospective study of a population of 153 patients receiving ICD (65 with CCC and 88 with IHD). The devices were implanted between 2003 and 2011. Survival rates and event-free survival were compared.

Results: The groups were similar regarding sex, functional class and ejection fraction. Ischemic patients were, on average, 10 years older than CCC patients (p < 0.05). Patients with CCC had lower schooling and monthly income than IHD patients (p < 0.05). The number of appropriate therapies was 2.07 higher in CCC patients, who had a greater incidence of appropriate shock (p < 0.05). Annual mortality rate and electrical storm incidence were similar in both groups. There was no sudden death in CCC patients, and only one in IHD patients. Neither survival time (p = 0.720) nor event-free survival (p = 0.143) significantly differed between the groups.

Conclusion: CCC doubles the risk of receiving appropriate therapies as compared to IHD, showing the greater complexity of arrhythmias in Chagas patients.

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Conflict of interest statement

Potential Conflict of Interest No potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1
Mean survival time [chronic Chagas cardiomyopathy (CCC) versus ischemic heart disease (IHD)]
Figure 2
Figure 2
Event-free survival time [chronic Chagas cardiomyopathy (CCC) versus ischemic heart disease (IHD)]
See this image and copyright information in PMC

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