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Comment
. 2016 Jun;5(3):343-6.
doi: 10.21037/tlcr.2016.03.05.

Alectinib-a new chapter in the management of ALK-positive lung cancer

Affiliations
Comment

Alectinib-a new chapter in the management of ALK-positive lung cancer

Justin F Gainor. Transl Lung Cancer Res. 2016 Jun.
No abstract available

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Conflict of interest statement

Conflicts of Interest: JF Gainor has served as a compensated consultant for Novartis, Merck, Clovis, Genentech-Roche, Bristol-Myers Squibb, Boehringer Ingelheim, Jounce Therapeutics, and Kyowa Hakko Kirin.

Comment on

References

    1. Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007;448:561-6. 10.1038/nature05945 - DOI - PubMed
    1. Shaw AT, Engelman JA. ALK in lung cancer: past, present, and future. J Clin Oncol 2013;31:1105-11. 10.1200/JCO.2012.44.5353 - DOI - PMC - PubMed
    1. Antoniu SA. Crizotinib for EML4-ALK positive lung adenocarcinoma: a hope for the advanced disease? Evaluation of Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 2010;363(18):1693-703. Expert Opin Ther Targets 2011;15:351-3. 10.1517/14728222.2011.550880 - DOI - PubMed
    1. Solomon BJ, Mok T, Kim DW, et al. First-line crizotinib versus chemotherapy in ALK-positive lung cancer. N Engl J Med 2014;371:2167-77. 10.1056/NEJMoa1408440 - DOI - PubMed
    1. Shaw AT, Kim DW, Nakagawa K, et al. Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. N Engl J Med 2013;368:2385-94. 10.1056/NEJMoa1214886 - DOI - PubMed

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