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Comment
. 2016 Jul 1;311(1):C160-1.
doi: 10.1152/ajpcell.00159.2016.

Reply to "Letter to the editor: Comments on Cornachione et al. (2016): "The increase in non-cross-bridge forces after stretch of activated striated muscle is related to titin isoforms"

Dilson E Rassier  1
Affiliations
Comment

Reply to "Letter to the editor: Comments on Cornachione et al. (2016): "The increase in non-cross-bridge forces after stretch of activated striated muscle is related to titin isoforms"

Dilson E Rassier. Am J Physiol Cell Physiol. .
No abstract available

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Figures

Fig. 2.
Fig. 2.
Four superimposed contractions produced by myofibrils isolated from the psoas (A), soleus (B), and ventricle (C) muscles. Black traces: isometric contractions and passive stretches performed in pCa 4.5 and 9.0, respectively. Red traces: stretches produced after full development in pCa 4.5. Blue traces: stretches applied in pCa 4.5 after myofibrils were treated with rigor-EDTA, gelsolin, and BB. Note the high signal-to-noise ratio in the force traces, which allows the detection of small force differences during the experiments. During the stretches in pCa 4.5, the force increased substantially, and after the stretch the force decreased to attain a steady state that was higher than the force obtained during isometric contractions at a similar length. During the stretches in pCa 4.5 after the myofibrils were treated with rigor-EDTA, gelsolin, and BB, the force was higher than that produced during stretches in pCa 9.0 for the psoas and soleus muscles, but not for the ventricle muscle.
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References

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