The First Fully Automated Molecular Diagnostic Panel for Meningitis and Encephalitis: How Well Does It Perform, and When Should It Be Used?
- PMID: 27413189
- PMCID: PMC5005496
- DOI: 10.1128/JCM.01255-16
The First Fully Automated Molecular Diagnostic Panel for Meningitis and Encephalitis: How Well Does It Perform, and When Should It Be Used?
Abstract
Rapid and accurate molecular diagnostic tests for the most common causes of infectious meningitis and encephalitis have the potential for high clinical impact. In this issue of the Journal of Clinical Microbiology, Leber et al. (J Clin Microbiol 54:2251-2261, 2016, http://dx.doi.org/10.1128/JCM.00730-16) report results from a large clinical study designed to prospectively assess the performance of the FilmArray meningitis/encephalitis panel compared to conventional methods.
Copyright © 2016, American Society for Microbiology. All Rights Reserved.
Comment on
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Multicenter Evaluation of BioFire FilmArray Meningitis/Encephalitis Panel for Detection of Bacteria, Viruses, and Yeast in Cerebrospinal Fluid Specimens.J Clin Microbiol. 2016 Sep;54(9):2251-61. doi: 10.1128/JCM.00730-16. Epub 2016 Jun 22. J Clin Microbiol. 2016. PMID: 27335149 Free PMC article.
References
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- Leber AL, Everhart K, Balada-Llasat J-M, Cullison J, Daly J, Holt S, Lephart P, Salimnia H, Schreckenberger PC, DesJarlais S, Reed SL, Chapin KC, LeBlanc L, Johnson JK, Soliven NL, Carroll K, Miller J-A, Dien Bard J, Mestas J, Bankowski M, Enomoto T, Hemmert AC, Bourzac K. 2016. Multicenter evaluation of the BioFire FilmArray meningitis/encephalitis panel for the detection of bacteria, viruses, and yeast in cerebrospinal fluid specimens. J Clin Microbiol 54:2251–2261. doi:10.1128/JCM.00730-16. - DOI - PMC - PubMed
-
- Wilen CB, Monaco CL, Hoppe-Bauer J, Jackups R Jr, Bucelli RC, Burnham CA. 2015. Criteria for reducing unnecessary testing for herpes simplex virus, varicella-zoster virus, cytomegalovirus, and enterovirus in cerebrospinal fluid samples from adults. J Clin Microbiol 53:887–895. doi:10.1128/JCM.03161-14. - DOI - PMC - PubMed
-
- Huang HR, Fan LC, Rajbanshi B, Xu JF. 2015. Evaluation of a new cryptococcal antigen lateral flow immunoassay in serum, cerebrospinal fluid and urine for the diagnosis of cryptococcosis: a meta-analysis and systematic review. PLoS One 10:e0127117. doi:10.1371/journal.pone.0127117. - DOI - PMC - PubMed
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