[Comparative studies of rheologic properties of erythrocyte concentrates in relation to a 6-week storage period in various preservative solutions]

Abstract

Buffycoat free red cell concentrates were stored at 4 degrees C for 42 days in CPD-A1 and two new red cell preservation solutions, PAGGS-Sorbitol and SAG-Mannitol. The rheological behaviour of the red cells was measured by viscometry of red cell suspensions (hematocrit 45%) at steady flow at various intervals during the storage period. The viscoelastic properties of the red cells were studied at oscillatory flow using an oscillation rheometer. The deformability of the red cells during storage was determined by measurement of the viscosity of hard packed cells at steady flow. The results show better red cell deformability during the entire storage period using the new solutions PAGGS-Sorbitol or SAG-Mannitol compared to the standard blood bank preservation solution CPD-A1.