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Editorial
. 2016 Sep;14(5):408-12.
doi: 10.2450/2016.0027-16. Epub 2016 Jun 29.

HyperLp(a)lipoproteinaemia: unmet need of diagnosis and treatment?

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Editorial

HyperLp(a)lipoproteinaemia: unmet need of diagnosis and treatment?

Claudia Stefanutti et al. Blood Transfus. 2016 Sep.
No abstract available

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Figures

Figure 1
Figure 1
Percentage change from the phase 2 parent study baseline at week 52 in apolipoprotein B (ApoB), lipoprotein(a) (Lp[a]), triglycerides, high-density lipoprotein cholesterol (HDL-C), and apolipoprotein A1 (ApoA1). The changes in lipid parameters from baseline in patients receiving evolocumab were all statistically significant (p<0.0001, except for the changes in triglycerides which were p<0.05). The reductions in lipid parameters were greater for patients receiving evolocumab+SOC vs SOC alone (p≤0.0002). Error bars represent the standard error. Data in parentheses represent interquartile ranges. Adapted from Koren et al.. SOC: standard of care.
Figure 2
Figure 2
Mean plasma Lp(a) and LDL-C levels at baseline, and before/after LA. Reproduced from Stefanutti et al. Lp(a): lipoprotein(a); LDL-C: low-density lipoprotein cholesterol; LA: lipoprotein apheresis.

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