Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2016 Aug;43(8):519-23.
doi: 10.1097/OLQ.0000000000000477.

Variations in Clinical Presentation of Ocular Syphilis: Case Series Reported From a Growing Epidemic in the United States

Grace E Marx  1 , Shireesha Dhanireddy, Jeanne M Marrazzo, Susan A Tuddenham, Anne M Rompalo, Peter A Leone, Charlotte A Gaydos, Cornelis A Rietmeijer
Affiliations
Case Reports

Variations in Clinical Presentation of Ocular Syphilis: Case Series Reported From a Growing Epidemic in the United States

Grace E Marx et al. Sex Transm Dis. 2016 Aug.

Abstract

Ocular syphilis, a form of neurosyphilis, has been increasingly diagnosed in the United States. This case series summarizes the course of 6 patients recently diagnosed with ocular syphilis, emphasizing the varied sociodemographic factors and the wide range of symptoms and outcomes that are seen in patients with this disease.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Case 1: Fluorescein angiogram of the right eye demonstrating optic disc leakage.
Figure 2
Figure 2
Case 1: Fundus photograph of the right optic disc demonstrating hyperemia, blurred disc margins and elevated retinal nerve fiber layer.
Figure 3
Figure 3
Case 5: Slit lamp photograph of the right eye showing a shallow anterior chamber, pigment and fibrin on the anterior lens capsule.
Figure 4
Figure 4
Case 5: Slit lamp photograph of the right eye showing iris bombe as delineated by the slit lamp beam with associated pigment and fibrin on the anterior lens capsule suggestive of chronic inflammation.
Figure 5
Figure 5
Case 5: Anterior segment photograph of the right eye showing a white conjunctiva, ciliary flush, iris-corneal touch, a small pupil, and pigment with fibrin on the anterior lens capsule.
See this image and copyright information in PMC

Comment in

References

    1. Woolston S, Cohen SE, Fanfair RN, et al. A Cluster of Ocular Syphilis Cases—Seattle, Washington, and San Francisco, California, 2014–2015. MMWR Morb Mortal Wkly Rep. 2015;64:1150–1151. - PMC - PubMed
    1. Patton ME, Su JR, Nelson R, et al. Primary and secondary syphilis— United States, 2005–2013. MMWR Morb Mortal Wkly Rep. 2014;63:402–406. - PMC - PubMed
    1. CDC. Clinical advisory: Ocular syphilis in the United States. Atlanta, GA: US Department of Health and Human Services, CDC; p. 2015. Available at http://www.cdc.gov/std/syphilis/clinicaladvisoryos2015.htm.
    1. Workowski KA, Bolan GA. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recomm Rep. 2015 No. RR-3. - PMC - PubMed

Publication types