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Review
. 2016 Aug;122(2):178-91.
doi: 10.1016/j.oooo.2016.04.003. Epub 2016 Apr 19.

Oral submucous fibrosis: a historical perspective and a review on etiology and pathogenesis

Wanninayake Mudiyanselage Tilakaratne  1 , Rasika Priyadharshani Ekanayaka  1 , Saman Warnakulasuriya  2
Affiliations
Review

Oral submucous fibrosis: a historical perspective and a review on etiology and pathogenesis

Wanninayake Mudiyanselage Tilakaratne et al. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Aug.

Abstract

Oral submucous fibrosis (OSF) is a chronic, insidious disease characterized by progressive submucosal fibrosis of the oral cavity and the oropharynx. People affected by this disease mostly live in south Asia, but migrants from these countries to the United States and Europe may present with OSF. We provide a historical background of the disease, and the objective of this review is to update the current knowledge on the etiology and etiopathogenesis of OSF.

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