Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Apr;21(3):165-8.
doi: 10.1007/BF02586560.

Multiple primary cancers and prolonged survival: familial colonic and endometrial cancers

H T Lynch, W A Bardawil, R E Harris, P M Lynch, H A Guirgis, J F Lynch

Multiple primary cancers and prolonged survival: familial colonic and endometrial cancers

H T Lynch et al. Dis Colon Rectum. 1978 Apr.

Abstract

We describe features of multiple cancers in a small kindred wherein a cluster of tumors affecting various anatomic sites has been observed among eight directline relatives. Three of these individuals have had two or more primary malignancies, and one woman showed a remarkable tolerance to invasive cancer, having had four histologically verified neoplasms (cancers of the ovary, endometrium, and colon, and myelogenous leukemia). The constellation of tumors occurring at an early age among relatives of the kindred supports a genetic etiology.

PubMed Disclaimer

Publication types

LinkOut - more resources