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. 2016 Jul 4;5(1):978.
doi: 10.1186/s40064-016-2653-z. eCollection 2016.

Interpretation of postmortem head computed tomography for non-traumatic in-hospital deaths by non-radiologists: a preliminary study

Asuka Araki  1 , Noriyoshi Ishikawa  1 , Saki Takami  1 , Nahoko Ishikawa  1 , Chika Amano  2 , Haruo Takeshita  3 , Riruke Maruyama  1
Affiliations

Interpretation of postmortem head computed tomography for non-traumatic in-hospital deaths by non-radiologists: a preliminary study

Asuka Araki et al. Springerplus. .

Abstract

Purpose: Postmortem computed tomography (PMCT) has recently become important to clarify the cause of death in forensic medicine. It has also been proven to be useful for in-hospital deaths to a certain extent when interpreted by radiologists. However, accuracy of the interpretations of PMCT by non-radiologists remains to be elucidated. Nevertheless, they are often required to write death certificates based on the findings of PMCT in the absence of radiologists in Japan. We compared the interpretations of postmortem head CT (PMCT-H) by non-radiologists with the autopsy findings.

Methods: This study included 13 patients who underwent both brain dissection at autopsy and PMCT between June 2011 and December 2014. All cases were non-traumatic in-hospital deaths. Interpretation of PMCT was performed by the clinicians in charge of the patients, not by radiology experts.

Results: The patients were first examined with PMCT and then autopsies were performed. Ten out of 13 cases were confirmed to have no lesions in the cranial cavity by both PMCT-H and autopsy. Two cases were diagnosed with intracranial hemorrhage (intracerebral and/or subarachnoid hemorrhage) and one with recurrent malignant lymphoma by both the clinicians and the pathologists. Intracranial hemorrhages were thought to be the direct causes of mortality of the two patients, and recurrent malignant lymphoma was considered to be one of the cardinal findings of the cancer death. There were no discrepancies between PMCT-H and autopsy findings.

Conclusions: The interpretations of PMCT-H by non-radiologists were completely the same as the autopsy findings regarding the non-traumatic in-hospital deaths in this study. It is premature to draw a definitive conclusion at present, but PMCT-H might be as effective as autopsy not only for those lesions described above but also for no remarkable changes in the brain. There has been no report on such a comparison. We believe further verification of the validity of interpretation of PMCT by non-radiologists is worthwhile in terms of death certificates made out in the absence of radiology experts and pathologists.

Keywords: Autopsy; Head; In-hospital death; Non-radiologist; Postmortem computed tomography.

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Figures

Fig. 1
Fig. 1
A 77 year-old-female who died of cerebral and subarachnoid hemorrhage (case no. 4). a Postmortem CT image through the brain showing cerebral hemorrhage with ventricular rupture and subarachnoid hemorrhage. b Macroscopic view of lower brain with subarachnoid hemorrhage. c Macroscopic view of a brain slice with cerebral and intraventricular hemorrhage. d Microscopic view of cerebral hemorrhage (hematoxylin and eosin)
Fig. 2
Fig. 2
A 77 year-old-male who died of recurrence of malignant lymphoma of diffuse large B-cell type (case no. 13). a Postmortem CT image through the brain showing low density area in the superior sagittal sinus and right transverse sinus, indicative of a space-occupying lesion. b Microscopic view of the sagittal sinus showing lymphoma cell infiltration
See this image and copyright information in PMC

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