Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017:32:165-181.
doi: 10.1007/7854_2016_32.

The Affective Properties of Synthetic Cathinones: Role of Reward and Aversion in Their Abuse

Heather E King  1 , Anthony L Riley  2
Affiliations
Review

The Affective Properties of Synthetic Cathinones: Role of Reward and Aversion in Their Abuse

Heather E King et al. Curr Top Behav Neurosci. 2017.

Abstract

The drug class known as synthetic cathinones has gained significant attention in the last few years as a result of increased use and abuse. These compounds have been shown to possess reinforcing efficacy in that they are abused in human populations and are self-administered in animal models. The present chapter outlines the affective properties of synthetic cathinones that are thought to impact drug self-administration in general and presents research confirming that these drugs have both rewarding and aversive effects in standalone and concurrent assessments. The implications of these affective properties for the overall abuse potential of these compounds are discussed along with directions for future research.

Keywords: Affective properties; Avoidance; Cathinones; Reward.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Baumann MH (2014) Awash in a sea of ‘bath salts’: implications for biomedical research and public health. Addiction 109(10):1577–1579 - PubMed - PMC
    1. Baumann MH, Partilla JS, Lehner KR (2013) Psychoactive “bath salts”: not so soothing. Eur J Pharmacol 698(1):1–5 - PubMed
    1. Katz DP, Bhattacharya D, Bhattacharya S, Deruiter J, Clark CR, Suppiramaniam V, Dhanasekaran M (2014) Synthetic cathinones: “a khat and mouse game”. Toxicol Lett 229(2):349–356 - PubMed
    1. Kyle PB, Iverson RB, Gajagowni RG, Spencer L (2011) Illicit bath salts: not for bathing. J Miss State Med Assoc 52(12):375–377 - PubMed
    1. Baumann MH, Solis E, Watterson LR, Marusich JA, Fantegrossi WE, Wiley JL (2014) Baths salts, spice, and related designer drugs: the science behind the headlines. J Neurosci 34(46):15150–15158 - PubMed - PMC

LinkOut - more resources