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Observational Study
. 2017 Aug;43(4):549-556.
doi: 10.1007/s00068-016-0708-z. Epub 2016 Jul 18.

Usability and effectiveness of Suprathel® in partial thickness burns in children

Z M Rashaan  1   2 , P Krijnen  3 , J H Allema  4 , A F Vloemans  5 , I B Schipper  3 , R S Breederveld  3   5   6
Affiliations
Observational Study

Usability and effectiveness of Suprathel® in partial thickness burns in children

Z M Rashaan et al. Eur J Trauma Emerg Surg. 2017 Aug.

Abstract

Purpose: Evaluation of usability and effectiveness of Suprathel® in the treatment of partial thickness burns in children.

Methods: A prospective, observational study to evaluate adherence of Suprathel® to the wound bed, reepithelialization time, grafting, wound colonization and infection, pain, dressing changes, length of hospital stay (LOS) and scar formation.

Results: Twenty-one children (median age 2.4 years, range 5 months-14 years) with a median total body surface area (TBSA) of 4 % (range 1-18) were included. Median LOS was 10 days (range 3-20). Median outer layer dressing changes was 3 (range 1-14). Suprathel® was only adherent in wounds debrided with Versajet®. Median reepithelialization time was 13 days (range 7-29). Three patients needed a split skin graft. There were 7 (33 %) patients with wound colonization before application of Suprathel®. This increased to 12 (57 %) patients during treatment. One patient developed a wound infection. Median visual analog scale (VAS) scores for background and procedural pain in patients >7 years were 3.2 (range 2-5) and 3.5 (range 2-5), respectively. In younger patients, median background and procedural COMFORT-B scores were 13.8 (range 10-23) and 14.8 (range 13-23, p = 0.03), respectively. Patient and Observer Scar Assessment Scale (POSAS) scores were favorable after 3 and 6 months post burn.

Conclusions: Suprathel® provides potential advantages regarding pain and scar formation, but extensive wound debridement is needed to achieve adequate adherence.

Keywords: Children; Effectiveness; Partial thickness burns; Suprathel®; Usability.

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Conflict of interest statement

Funding

This project was funded by Dutch Burns Foundation (WO/12.109) and initiated by the Leiden Medical University Center (LUMC).

Ethical approval

The local ethics committees approved our study (Reference No.: 2012–346). All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Parents of the included pediatric patients gave informed consent prior to the inclusion in the study.

Conflict of interest

Z. M. Rashaan, P. Krijnen, J. H. Allema, A. F. P. Vloemans, I. B. Schipper and R. S. Breederveld declare that they have no conflict of interest.

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