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. 2016 Jul 19;11(7):e0159519.
doi: 10.1371/journal.pone.0159519. eCollection 2016.

A Shortest-Path-Based Method for the Analysis and Prediction of Fruit-Related Genes in Arabidopsis thaliana

Liucun Zhu  1 , Yu-Hang Zhang  2 , Fangchu Su  1 , Lei Chen  3 , Tao Huang  2 , Yu-Dong Cai  1
Affiliations

A Shortest-Path-Based Method for the Analysis and Prediction of Fruit-Related Genes in Arabidopsis thaliana

Liucun Zhu et al. PLoS One. .

Abstract

Biologically, fruits are defined as seed-bearing reproductive structures in angiosperms that develop from the ovary. The fertilization, development and maturation of fruits are crucial for plant reproduction and are precisely regulated by intrinsic genetic regulatory factors. In this study, we used Arabidopsis thaliana as a model organism and attempted to identify novel genes related to fruit-associated biological processes. Specifically, using validated genes, we applied a shortest-path-based method to identify several novel genes in a large network constructed using the protein-protein interactions observed in Arabidopsis thaliana. The described analyses indicate that several of the discovered genes are associated with fruit fertilization, development and maturation in Arabidopsis thaliana.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Procedures of and results obtained using the shortest-path-based method for the identification of novel fruit-related genes in Arabidopsis thaliana.
See this image and copyright information in PMC

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