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Case Reports
. 1989 May;56(3):253-7.
doi: 10.3949/ccjm.56.3.253.

Methotrexate for corticosteroid-resistant polymyalgia rheumatica and giant cell arteritis

P L Krall, D J Mazanec, W S Wilke
Free article
Case Reports

Methotrexate for corticosteroid-resistant polymyalgia rheumatica and giant cell arteritis

P L Krall et al. Cleve Clin J Med. 1989 May.
Free article

Abstract

Three patients (one with polymyalgia rheumatica with jaw claudication and two with biopsy-proven giant cell arteritis) were initially treated using prednisone (40-60 mg daily). The response was good in all three, but each experienced exacerbation of symptoms and elevation of Westergren sedimentation rates (WSR) with dose reduction. The addition of methotrexate (7.5-12.5 mg/wk) resulted in diminished symptoms and lower WSR and proved to be steroid-sparing.

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