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. 2016:2016:5926307.
doi: 10.1155/2016/5926307. Epub 2016 Jun 30.

A Challenging Giant Dermatofibrosarcoma Protuberans on the Face

Gimena Castro Pérez  1 , Cintia Arias  1 , Paula Luna  2 , Irene Sorín  3 , Luis Daniel Mazzuoccolo  1
Affiliations

A Challenging Giant Dermatofibrosarcoma Protuberans on the Face

Gimena Castro Pérez et al. Case Rep Dermatol Med. 2016.

Abstract

Dermatofibrosarcoma protuberans (DFSP) is a malignant fibrohistiocytic tumor that appears exclusively on the skin. It is a low-grade malignant soft tissue tumor of subcutaneous tissues that has a propensity for local recurrence but seldom metastasizes. It may rarely occur on the head and neck accounting for less than one percent of total head and neck malignancies. We present a man with a giant DFSP on the face. Oncological, functional, and aesthetic aspects are set forth.

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Figures

Figure 1
Figure 1
A dome-shaped, skin-colored, with smooth surface, firm tumor furrowed by telangiectasias.
Figure 2
Figure 2
H&E panoramic view. Cutaneous section showing a dermal cell proliferation that leaves a free Grenz zone.
Figure 3
Figure 3
H&E 40x. Dermal infiltrate with low mitotic rate. Spindle cells mimicking a storiform pattern.
Figure 4
Figure 4
Immunohistochemistry demonstrated diffusely positive staining for CD34 (a) and vimentin (b) and negative staining for smooth muscle actin (c) consistent with DFSP.
Figure 5
Figure 5
Follow-up at 36 months showing no signs of recurrence and marked disfigurement.
See this image and copyright information in PMC

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