Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2016 May;10(5):ED16-7.
doi: 10.7860/JCDR/2016/15691.7836. Epub 2016 May 1.

Basaloid Squamous Cell Carcinoma of Scalp From A Pre-Existing Cylindroma Metastasising To Brain: A Rare Case Report

Impana Bellavara Diwakar  1 , Teerthanath Srinivas  2 , Jayaram Shetty Kolakebail  3 , Jayaprakash Shetty  4 , Prachi Kukreja  1
Affiliations
Case Reports

Basaloid Squamous Cell Carcinoma of Scalp From A Pre-Existing Cylindroma Metastasising To Brain: A Rare Case Report

Impana Bellavara Diwakar et al. J Clin Diagn Res. 2016 May.

Abstract

Squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer and accounts for 90% of head and neck malignancies. Intracranial metastases of SCC are extremely rare. We are reporting a case of 55-year-old female with history of recurrent swelling over right side of forehead which was previously reported as cylindroma. CT scan of head revealed irregular lytic areas in right frontal bone suggestive of erosion. There were multiple small, rim enhancing lesions in bilateral parietal regions. Clinically it was diagnosed as malignant adnexal tumour. Wide excision of the lesion revealed features of invasive basaloid squamous cell carcinoma, probably a malignant transformation of the pre-existing cylindroma.

Keywords: Adnexal tumour; Brain metastasis; Non-melanoma skin malignancy.

PubMed Disclaimer

Figures

[Table/Fig-1]:
[Table/Fig-1]:
Malignant ulcers over forehead.
[Table/Fig-2]:
[Table/Fig-2]:
X-ray showing lytic lesions in frontal bone.
[Table/Fig-3]:
[Table/Fig-3]:
CT scan showing erosion of the frontal bone with underlying heterogeneously enhancing mass with central hypodense area in right frontal bone.
[Table/Fig-4]:
[Table/Fig-4]:
Tumour cells showing peripheral palisading arrangement (H&E X 400) Inset showing infiltrating basaloid squamous cell carcinoma (H&E X 100).
See this image and copyright information in PMC

References

    1. Sicinska J, Rakowska A, Czuwara-Ladykowska J, Mroz A, Lipinski M, Nasierowska-Guttmejer A, et al. Cylindroma transforming into basal cell carcinoma in a patient with Brooke -Spiegler syndrome. J Dermatol Case Rep. 2007;1:4–9. - PMC - PubMed
    1. Obaidat NA, Alsaad KO, Ghazarian D. Skin adnexal neoplasms - part 2: An approach to tumours of cutaneous sweat glands. J Clin Patho. 2007;60(2):145–59. - PMC - PubMed
    1. Gurudutt VV, Genden EM. Cutaneous squamous cell carcinoma of the head and neck. J Skin Cancer. 2011;2011:1–32. - PMC - PubMed
    1. Vinicius Vazquez, Sergio Serrano and Renato Capuzzo (2012). Advanced Squamous Cell Carcinoma of the Skin, Squamous Cell Carcinoma, Prof. Xiaoming Li (Ed.), ISBN: 978-953-51-0024-9, InTech, Available from: http://www.intechopen.com/books/squamous-cell-carcinoma/advanced-squamou....
    1. Taheri MS, Talebnejad S, Birang SH, Nahvi V. Malignant transformation of multiple dermal cylindromas. Iran J Radiol. 2005;3(1):99–101.

Publication types

LinkOut - more resources