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Review
. 2016 Sep;16(9):77.
doi: 10.1007/s11910-016-0684-z.

Anosognosia in Dementia

Robert S Wilson  1   2   3 , Joel Sytsma  4 , Lisa L Barnes  4   5   6 , Patricia A Boyle  4   6
Affiliations
Review

Anosognosia in Dementia

Robert S Wilson et al. Curr Neurol Neurosci Rep. 2016 Sep.

Abstract

Progressive decline in memory (and other functions) is the defining feature of late-life dementia but affected individuals are often unaware of this impairment. This article reviews recent research on anosognosia in dementia, including methods of assessing anosognosia, its prevalence and developmental course in dementia, its occurrence in different forms of dementia, neuroimaging findings, and hypothesized component mechanisms. The results suggest that anosognosia is eventually exhibited by nearly all persons with dementia. Its occurrence is robustly associated with common dementia-related pathologies and damage to memory and self-referential brain networks and their interconnections.

Keywords: Anosognosia; Dementia; Frontotemporal dementia; Memory awareness; Metacognition; Subjective memory.

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References

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