DBS for Obesity
- PMID: 27438859
- PMCID: PMC5039450
- DOI: 10.3390/brainsci6030021
DBS for Obesity
Abstract
Obesity is a chronic, progressive and prevalent disorder. Morbid obesity, in particular, is associated with numerous comorbidities and early mortality. In patients with morbid obesity, pharmacological and behavioral approaches often have limited results. Bariatric surgery is quite effective but is associated with operative failures and a non-negligible incidence of side effects. In the last decades, deep brain stimulation (DBS) has been investigated as a neurosurgical modality to treat various neuropsychiatric disorders. In this article we review the rationale for selecting different brain targets, surgical results and future perspectives for the use of DBS in medically refractory obesity.
Keywords: deep brain stimulation; hypothalamus; nucleus accumbens; obesity.
Conflict of interest statement
The authors declare no conflict of interest.
References
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