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. 2017 Mar;47(3):284-292.
doi: 10.1007/s00595-016-1386-5. Epub 2016 Jul 21.

Surgery for non-small cell lung cancer in patients with a history of cardiovascular surgery

Hideyuki Maeda  1 , Masato Kanzaki  2 , Kei Sakamoto  1 , Tamami Isaka  1 , Kenji Yamazaki  3 , Takamasa Onuki  1
Affiliations

Surgery for non-small cell lung cancer in patients with a history of cardiovascular surgery

Hideyuki Maeda et al. Surg Today. 2017 Mar.

Abstract

Purpose: To clarify if previous cardiovascular surgery (CVS) affects the postoperative outcome of surgery for non-small cell lung cancer (NSCLC).

Methods: We reviewed, retrospectively, the medical records of 36 patients with a history of CVS, who underwent lung cancer surgery at a single institution (study group; SG) and compared their characteristics and postoperative outcomes with those of patients without a history of CVS history (control group; CG), and also with those of patients with coexisting cardiovascular diseases in the CG (specified control group; SCG). Finally, we used a thoracic revised cardiac risk index (ThRCRI) to evaluate the risk of perioperative cardiovascular events.

Results: There was a significant difference in the ThRCRI classifications between the SG and the SCG (p < 0.0001). There were no significant differences in the incidence of intraoperative and postoperative complications between the SG and CG, or between the SG and SCG. The 5-year survival rates of the SG, CG, and SCG were 69.3, 73.9, and 65.4 % in all stages, and 83.5, 82.2, and 70.4 % in stage I, respectively.

Conclusions: Previous CVS did not increase the number of perioperative cardiovascular events in this study and had no significant influence on the prognosis of patients undergoing resection of NSCLC.

Keywords: Cardiovascular surgery; Lung cancer; Surgery.

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Conflict of interest statement

Conflicts of Interest: None declared.

Figures

Fig. 1
Fig. 1
The survival curves of all stages and stage I of the two sets of two groups, which were the study group (SG) vs. the control group (CG), SG vs. the specified control group (SCG). a The 5-year survival rates of patients with all stages of lung cancer; 69.3 % in SG (red line, n = 31) and 73.9 % in CG (blue line, n = 994). b The 5-year survival rates of patients with stage I lung cancer; 83.5 % in SG (red line, n = 23) and 82.2 % in CG (blue line, n = 682). c The 5-year survival rates of patients with all stages of lung cancer; 69.3 % in SG (red line, n = 31) and 65.4 % in SCG (blue line, n = 135). d The 5-year survival rates of patients with stage I lung cancer; 83.5 % in SG (red line, n = 23) and 70.4 % in SCG (blue line, n = 102)
See this image and copyright information in PMC

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