Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Oct;86(2):221-3.
doi: 10.1016/j.diagmicrobio.2016.07.005. Epub 2016 Jul 8.

Emergence of Mycoplasma genitalium strains showing mutations associated with macrolide and fluoroquinolone resistance in the region Dresden, Germany

Roger Dumke  1 , Alexander Thürmer  2 , Enno Jacobs  2
Affiliations

Emergence of Mycoplasma genitalium strains showing mutations associated with macrolide and fluoroquinolone resistance in the region Dresden, Germany

Roger Dumke et al. Diagn Microbiol Infect Dis. 2016 Oct.

Abstract

Among 323 specimens from male patients with symptoms of non-gonococcal urethritis, Mycoplasma genitalium was detected in 19 samples by real-time PCR. Mutations of 23S rRNA gene associated with macrolide resistance were confirmed in 10 strains. Amino acid changes at positions 81 and 83 of ParC protein were demonstrated indicating quinolone resistance of two strains.

Keywords: 23S rRNA mutation; Genotyping; Macrolide resistance; Mycoplasma genitalium; Quinolone resistance; Topoisomerase mutation.

PubMed Disclaimer

MeSH terms

LinkOut - more resources