In vivo antigenic variation of Campylobacter flagellin
- PMID: 2744863
- PMCID: PMC313492
- DOI: 10.1128/iai.57.8.2583-2585.1989
In vivo antigenic variation of Campylobacter flagellin
Abstract
Campylobacter coli VC167 cells producing either antigenic phase 1 (P1) or phase 2 (P2) flagellins (as determined by characteristic protein and DNA patterns) were used to infect rabbits by the removable intestinal tie-adult rabbit diarrhea (RITARD) procedure. Rabbits infected with P2 cells shed predominantly P2 cells throughout the infection; in rabbits infected with P1 cells, a transition of fecal isolates from P1 to P2 was observed.
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