Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1989 Jan;27(1):47-50.

Motor effects of locally administered pinaverium bromide in the sigmoid tract of patients with irritable bowel syndrome

S Passaretti  1 , M Sorghi, E Colombo, G Mazzotti, A Tittobello, M Guslandi
Affiliations
  • PMID: 2744907
Clinical Trial

Motor effects of locally administered pinaverium bromide in the sigmoid tract of patients with irritable bowel syndrome

S Passaretti et al. Int J Clin Pharmacol Ther Toxicol. 1989 Jan.

Abstract

The effects of pinaverium bromide, a non-absorbable antispasmodic agent, administered locally, on sigmoid-rectal motility was investigated in 20 patients with irritable bowel syndrome. The influence of either pinaverium (10 subjects) or placebo (10 subjects) on a neostigmine-induced increase of sigmoid pressure was assessed and compared by means of computerized electromanometry. The drug was found to counteract significantly the motor effects of neostigmine, thus appearing to be an effective compound for the treatment of functional disorders of the colon.

PubMed Disclaimer

Publication types

LinkOut - more resources