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Comment
. 2016 Aug;136(8):1535-1537.
doi: 10.1016/j.jid.2016.04.031.

Research that Guides Clinical Decisions

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Research that Guides Clinical Decisions

Mary-Margaret Chren et al. J Invest Dermatol. 2016 Aug.
Free article

Abstract

The centerpiece of evidence-based medicine is the randomized controlled trial, a rigorous experiment. We use the study by Roozeboom et al. to illustrate how research guides clinical decisions. We describe levels of evidence, review criteria for assessing a trial regarding noninferiority of a therapy, and discuss challenges for evidence-based medicine in guiding care precisely targeted to an individual patient.

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