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Case Reports
. 2016 Apr;63(2):130-2.
doi: 10.1016/j.ijtb.2015.07.009. Epub 2016 Jun 4.

An outbreak of multidrug-resistant tuberculosis among a family

Sinem Iliaz  1 , Emel Caglar  2 , Orhan Kaya Koksalan  3 , Efsun Gonca Ugur Chousein  2
Affiliations
Case Reports

An outbreak of multidrug-resistant tuberculosis among a family

Sinem Iliaz et al. Indian J Tuberc. 2016 Apr.

Abstract

Tuberculosis is a major public health problem and it may be complicated by multidrug-resistant tuberculosis (MDR-TB). Wide transmission among immunocompetent contacts of the index case is possible. If you detect tuberculosis in two contacts of the index case, it is called an outbreak. The aim of our paper is to evaluate the characteristics of a MDR-TB outbreak affecting 7 people in a family treated during 2012-2014 in Istanbul Yedikule Training and Research Hospital for Chest Disease and Thoracic Surgery, Turkey. The cultures, spoligotyping, and DNA fingerprinting revealed the same Mycobacterium tuberculosis species as T1 genotype and ST53 subtype. All patients were negative for human immunodeficiency virus and free of other underlying diseases.

Keywords: Contact; Multidrug resistance; Transmission; Tuberculosis.

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