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Case Reports
. 2016 Jul-Sep;8(3):381-3.
doi: 10.4103/0974-7796.184897.

Plasmacytoid urothelial carcinoma of the bladder with extensive scrotal wall invasion

Affiliations
Case Reports

Plasmacytoid urothelial carcinoma of the bladder with extensive scrotal wall invasion

Yong Gang Wang et al. Urol Ann. 2016 Jul-Sep.

Abstract

Plasmacytoid urothelial carcinoma (PUC) is an extremely rare and aggressive variant of urothelial carcinoma. We report a case of a 62-year-old male who presented with a rapid spread of PUC to involve his entire scrotal wall after failed surgery and chemotherapy. The second course of chemotherapy was effective in providing symptom control. We believe this is the first case report of PUC causing such rapid and extensive scrotal invasion. This case highlights the important features of PUC including the pattern of tumor spread along fascial planes, the tendency for initial understaging, and the rapid recurrence after initially response to chemotherapy.

Keywords: Plasmacytoid; scrotal spread; urothelial carcinoma.

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Figures

Figure 1
Figure 1
Histology from original specimen showing plasmacytoid urothelial carcinoma
Figure 2
Figure 2
Clinical appearance of scrotum
Figure 3
Figure 3
Magnetic resonance imaging of scrotum (T1-weighted images) showing extensive thickening of tissues extending down from inguinal canal
Figure 4
Figure 4
Scrotal biopsy specimen with infiltration by plasmacytoid urothelial carcinoma

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References

    1. Sahin AA, Myhre M, Ro JY, Sneige N, Dekmezian RH, Ayala AG. Plasmacytoid transitional cell carcinoma. Report of a case with initial presentation mimicking multiple myeloma. Acta Cytol. 1991;35:277–80. - PubMed
    1. Keck B, Stoehr R, Wach S, Rogler A, Hofstaedter F, Lehmann J, et al. The plasmacytoid carcinoma of the bladder – Rare variant of aggressive urothelial carcinoma. Int J Cancer. 2011;129:346–54. - PubMed
    1. Dayyani F, Czerniak BA, Sircar K, Munsell MF, Millikan RE, Dinney CP, et al. Plasmacytoid urothelial carcinoma, a chemosensitive cancer with poor prognosis, and peritoneal carcinomatosis. J Urol. 2013;189:1656–61. - PMC - PubMed
    1. Keck B, Wach S, Stoehr R, Kunath F, Bertz S, Lehmann J, et al. Plasmacytoid variant of bladder cancer defines patients with poor prognosis if treated with cystectomy and adjuvant cisplatin-based chemotherapy. BMC Cancer. 2013;13:71. - PMC - PubMed
    1. Wang Z, Lu T, Du L, Hu Z, Zhuang Q, Li Y, et al. Plasmacytoid urothelial carcinoma of the urinary bladder: A clinical pathological study and literature review. Int J Clin Exp Pathol. 2012;5:601–8. - PMC - PubMed

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