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Case Reports
. 2016 Jan-Mar;5(1):160-2.
doi: 10.4103/2249-4863.184643.

Warfarin-induced leukocytoclastic vasculitis and proteinuria

Khalid Jumean  1 , Ahmad Abu Arqoub  1 , Amer Hawatmeh  1 , Firas Qaqa  1 , Ayham Bataineh  1 , Hamid Shaaban  1
Affiliations
Case Reports

Warfarin-induced leukocytoclastic vasculitis and proteinuria

Khalid Jumean et al. J Family Med Prim Care. 2016 Jan-Mar.

Abstract

Warfarin is typically prescribed for patients with thromboembolic diseases and atrial fibrillation. In addition to the complications of bleeding, allergic skin reaction is one of its rare adverse effects. We herein report a case of a 79 year old male patient with leukocytoclastic vasculitis and proteinuria secondary to warfarin. The warfarin was discontinued and oral prednisone therapy was initiated. The cutaneous lesions and the proteinuria resolved thereafter.

Keywords: Leukocytoclastic; proteinuria; vasculitis; warfarin.

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Figures

Figure 1
Figure 1
(a) Physical examination revealed bilateral lower extremities (from ankle to mid-thigh) and palpable purpura. (b) Examination of lower extremities revealed pupura
Figure 2
Figure 2
(a) low field and (b) high field. Histopathology revealed perivascular and interstitial inflammation involving small blood vessels, with predominantly neutrophilic infiltration and extravasation admixed with few eosinophils
See this image and copyright information in PMC

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