. 2016 Jul 18;17 Suppl 1(Suppl 1):311.

doi: 10.1186/s13063-016-1436-8.

Proceedings of the First International Conference on Stepped Wedge Trial Design : York, UK, 10 March 2016

Mona Kanaan¹, Noreen Dadirai Mdege¹, Ada Keding¹, RA Parker², N. Mills³, A. Shah³, F. Strachan², C. Keerie², C. J. Weir², Andrew Forbes⁴, Karla Hemming⁵, Sarah A. Lawton⁶, Emma Healey⁶, Martyn Lewis⁶, Elaine Nicholls⁶, Clare Jinks⁶, Valerie Tan⁶, Andrew Finney⁶, Christian D. Mallen⁶; on behalf of the ENHANCE Study Team; Erik Lenguerrand⁷, Graeme MacLennan⁸, John Norrie⁸, Siladitya Bhattacharya⁹, Tim Draycott¹⁰; on behalf of the Thistle group; Richard Hooper¹¹, Steven Teerenstra¹², Esther de Hoop¹³, Sandra Eldridge¹¹, Alan Girling¹⁴, Monica Taljaard¹⁵, Gian Luca Di Tanna¹⁶, Antonio Gasparrini¹⁶, Anna Casula¹⁷, Fergus Caskey^{17

18}, Erik Lenguerrand¹⁹, Shona Methven^{17

19}, Stephanie MacNeill^{17

18}, Margaret May¹⁸, Nicholas Selby^{20

21}, Leon Danon²², Hannah Christensen²², Adam Finn²³, Margaret May²², Fumihito Takanashi¹, Ada Keding¹, Simon Crouch¹, Mona Kanaan¹, Caroline A. Kristunas²⁴, Karen L. Smith²⁵, Laura J. Gray²⁵, John N.S. Matthews²⁶, R. Al-Shahi Salman²⁷, R. A. Parker², A. Maxwell²⁷, M. Dennis²⁷, A. Rudd²⁸, C. J. Weir², Jennifer A. Thompson^{29

30}, Katherine L. Fielding²⁹, Calum Davey³¹, Alexander M. Aiken³¹, James R. Hargreaves³¹, Richard J. Hayes²⁹, Vivian H. Lyons^{32

33}, Lingyu Li³⁴, James Hughes³⁴, Ali Rowhani-Rahbar^{32

33}, Karla Hemming³⁵, Monica Taljaard^{36

37}, Andrew Forbes³⁸

Affiliations

¹ Department of Health Sciences, University of York, York, North Yorkshire YO10 5DD UK
² Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Medical School, Teviot Place, Edinburgh, EH8 9AG UK
³ British Heart Foundation Centre for Cardiovascular Sciences, Chancellors Building, The University of Edinburgh, Edinburgh, EH16 4SB UK
⁴ School of Public Health and Preventive Medicine, Monash University, Melbourne, Melbourne, Australia
⁵ Department of Public Health, Epidemiology and Biostatistics, University of Birmingham, Birmingham, UK
⁶ Research Institute for Primary Care & Health Sciences, Keele University, Keele, Staffs UK
⁷ School of Clinical Sciences, University of Bristol, Bristol, BS105NB UK
⁸ Centre for Healthcare Randomised Trials, University of Aberdeen, Aberdeen, AB252ZD UK
⁹ Applied Health Sciences School of Medicine and Dentistry, University of Aberdeen, Aberdeen, AB252ZD UK
¹⁰ School of Social and Community Medicine, University of Bristol, Bristol, BS105NB UK
¹¹ Centre for Primary Care & Public Health, Queen Mary University of London, London, UK
¹² Radboud Institute for Health Sciences, Radboud University Medical Centre, Nijmegen, Netherlands
¹³ Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, Netherlands
¹⁴ Institute of Applied Health Research, University of Birmingham, Birmingham, B15 2TT UK
¹⁵ School of Epidemiology, Public Health, and Preventive Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5 Canada
¹⁶ London School of Hygiene and Tropical Medicine, London, WC1E 7HT UK
¹⁷ UK Renal Registry, Bristol, BS10 5NB UK
¹⁸ School of Social and Community Medicine, University of Bristol, Bristol, BS8 2PS UK
¹⁹ School of Clinical Sciences, University of Bristol, Bristol, BS10 5NB UK
²⁰ Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, NG7 2UH UK
²¹ Royal Derby Hospital, Derby, DE22 3DT UK
²² School of Social and Community Medicine, University of Bristol, Bristol, BS8 2BN UK
²³ School of Cellular and Molecular Medicine, University of Bristol, Bristol, BS2 8AE UK
²⁴ Diabetes Research Centre, University of Leicester, Leicester, UK
²⁵ Department of Health Sciences, University of Leicester, Leicester, UK
²⁶ School of Mathematics & Statistics, Newcastle University, Newcastle upon Tyne, NE1 7RU UK
²⁷ Centre for Clinical Brian Sciences, The University of Edinburgh, Edinburgh, UK
²⁸ Sentinel Stroke National Audit Programme, Royal College of Physicians, London, UK
²⁹ Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK
³⁰ London Hub for Trials Methodology Research, MRC Clinical Trials Unit at University College London, London, UK
³¹ Department of Social and Environmental Health Research, London School of Hygiene and Tropical Medicine, London, UK
³² Department of Epidemiology, University of Washington, Seattle, WA USA
³³ Harborview Injury Prevention & Research Center, Seattle, WA USA
³⁴ Department of Biostatistics, University of Washington, Seattle, WA USA
³⁵ School of Health and Population Sciences, University of Birmingham, Birmingham, B15 2TT UK
³⁶ Clinical Epidemiology Program, Ottawa Hospital Research Institute, 1053 Carling Avenue, Ottawa, Ontario K1Y4E9 Canada
³⁷ Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario Canada
³⁸ School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

PMID: 27454562
PMCID: PMC4959349
DOI: 10.1186/s13063-016-1436-8

Proceedings of the First International Conference on Stepped Wedge Trial Design : York, UK, 10 March 2016

Mona Kanaan et al. Trials. 2016.

. 2016 Jul 18;17 Suppl 1(Suppl 1):311.

doi: 10.1186/s13063-016-1436-8.

Authors

Affiliations

¹ Department of Health Sciences, University of York, York, North Yorkshire YO10 5DD UK
² Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Medical School, Teviot Place, Edinburgh, EH8 9AG UK
³ British Heart Foundation Centre for Cardiovascular Sciences, Chancellors Building, The University of Edinburgh, Edinburgh, EH16 4SB UK
⁴ School of Public Health and Preventive Medicine, Monash University, Melbourne, Melbourne, Australia
⁵ Department of Public Health, Epidemiology and Biostatistics, University of Birmingham, Birmingham, UK
⁶ Research Institute for Primary Care & Health Sciences, Keele University, Keele, Staffs UK
⁷ School of Clinical Sciences, University of Bristol, Bristol, BS105NB UK
⁸ Centre for Healthcare Randomised Trials, University of Aberdeen, Aberdeen, AB252ZD UK
⁹ Applied Health Sciences School of Medicine and Dentistry, University of Aberdeen, Aberdeen, AB252ZD UK
¹⁰ School of Social and Community Medicine, University of Bristol, Bristol, BS105NB UK
¹¹ Centre for Primary Care & Public Health, Queen Mary University of London, London, UK
¹² Radboud Institute for Health Sciences, Radboud University Medical Centre, Nijmegen, Netherlands
¹³ Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, Netherlands
¹⁴ Institute of Applied Health Research, University of Birmingham, Birmingham, B15 2TT UK
¹⁵ School of Epidemiology, Public Health, and Preventive Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5 Canada
¹⁶ London School of Hygiene and Tropical Medicine, London, WC1E 7HT UK
¹⁷ UK Renal Registry, Bristol, BS10 5NB UK
¹⁸ School of Social and Community Medicine, University of Bristol, Bristol, BS8 2PS UK
¹⁹ School of Clinical Sciences, University of Bristol, Bristol, BS10 5NB UK
²⁰ Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, NG7 2UH UK
²¹ Royal Derby Hospital, Derby, DE22 3DT UK
²² School of Social and Community Medicine, University of Bristol, Bristol, BS8 2BN UK
²³ School of Cellular and Molecular Medicine, University of Bristol, Bristol, BS2 8AE UK
²⁴ Diabetes Research Centre, University of Leicester, Leicester, UK
²⁵ Department of Health Sciences, University of Leicester, Leicester, UK
²⁶ School of Mathematics & Statistics, Newcastle University, Newcastle upon Tyne, NE1 7RU UK
²⁷ Centre for Clinical Brian Sciences, The University of Edinburgh, Edinburgh, UK
²⁸ Sentinel Stroke National Audit Programme, Royal College of Physicians, London, UK
²⁹ Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK
³⁰ London Hub for Trials Methodology Research, MRC Clinical Trials Unit at University College London, London, UK
³¹ Department of Social and Environmental Health Research, London School of Hygiene and Tropical Medicine, London, UK
³² Department of Epidemiology, University of Washington, Seattle, WA USA
³³ Harborview Injury Prevention & Research Center, Seattle, WA USA
³⁴ Department of Biostatistics, University of Washington, Seattle, WA USA
³⁵ School of Health and Population Sciences, University of Birmingham, Birmingham, B15 2TT UK
³⁶ Clinical Epidemiology Program, Ottawa Hospital Research Institute, 1053 Carling Avenue, Ottawa, Ontario K1Y4E9 Canada
³⁷ Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario Canada
³⁸ School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

PMID: 27454562
PMCID: PMC4959349
DOI: 10.1186/s13063-016-1436-8

Abstract

I1 Introduction

Mona Kanaan, Noreen Dadirai Mdege, Ada Keding

O1 The HiSTORIC trial: a hybrid before-and-after and stepped wedge design

RA Parker, N Mills, A Shah, F Strachan, C Keerie, CJ Weir

O2 Stepped wedge trials with non-uniform correlation structure

Andrew Forbes, Karla Hemming

O3 Challenges and solutions for the operationalisation of the ENHANCE study: a pilot stepped wedge trial within a general practice setting

Sarah A Lawton, Emma Healey, Martyn Lewis, Elaine Nicholls, Clare Jinks, Valerie Tan, Andrew Finney, Christian D Mallen, on behalf of the ENHANCE Study Team

O4 Early lessons from the implementation of a stepped wedge trial design investigating the effectiveness of a training intervention in busy health care settings: the Thistle study

Erik Lenguerrand, Graeme MacLennan, John Norrie, Siladitya Bhattacharya, Tim Draycott, on behalf of the Thistle group

O5 Sample size calculation for longitudinal cluster randomised trials: a unified framework for closed cohort and repeated cross-section designs

Richard Hooper, Steven Teerenstra, Esther de Hoop, Sandra Eldridge

O6 Restricted randomisation schemes for stepped-wedge studies with a cluster-level covariate

Alan Girling, Monica Taljaard

O7 A flexible modelling of the time trend for the analysis of stepped wedge trials: results of a simulation study

Gian Luca Di Tanna, Antonio Gasparrini

P1 Tackling acute kidney injury – a UK stepped wedge clinical trial of hospital-level quality improvement interventions

Anna Casula, Fergus Caskey, Erik Lenguerrand, Shona Methven, Stephanie MacNeill, Margaret May, Nicholas Selby

P2 Sample size considerations for quantifying secondary bacterial transmission in a stepped wedge trial of influenza vaccine

Leon Danon, Hannah Christensen, Adam Finn, Margaret May

P3 Sample size calculation for time-to-event data in stepped wedge cluster randomised trials

Fumihito Takanashi, Ada Keding, Simon Crouch, Mona Kanaan

P4 Sample size calculations for stepped-wedge cluster randomised trials with unequal cluster sizes

Caroline A. Kristunas, Karen L. Smith, Laura J. Gray

P5 The design of stepped wedge trials with unequal cluster sizes

John N.S. Matthews

P6 Promoting Recruitment using Information Management Efficiently (PRIME): a stepped wedge SWAT (study-within-a-trial)

R Al-Shahi Salman, RA Parker, A Maxwell, M Dennis, A Rudd, CJ Weir

P7 Implications of misspecified mixed effect models in stepped wedge trial analysis: how wrong can it be?

Jennifer A Thompson, Katherine L Fielding, Calum Davey, Alexander M Aiken, James R Hargreaves, Richard J Hayes

S1 Stepped Wedge Designs with Multiple Interventions

Vivian H Lyons, Lingyu Li, James Hughes, Ali Rowhani-Rahbar

S2 Analysis of the cross-sectional stepped wedge cluster randomised trial

Karla Hemming, Monica Taljaard, Andrew Forbes

PubMed Disclaimer

LinkOut - more resources

Full Text Sources
Other Literature Sources
- scite Smart Citations
Research Materials
- NCI CPTC Antibody Characterization Program
Miscellaneous
- NCI CPTAC Assay Portal

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Proceedings of the First International Conference on Stepped Wedge Trial Design : York, UK, 10 March 2016

Affiliations

Proceedings of the First International Conference on Stepped Wedge Trial Design : York, UK, 10 March 2016

Authors

Affiliations

Abstract

LinkOut - more resources

Full Text Sources

Other Literature Sources

Research Materials

Miscellaneous