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. 1989 May;27(5):1099-101.
doi: 10.1128/jcm.27.5.1099-1101.1989.

Detection of antigens in urine during acute toxoplasmosis

J Huskinson  1 , P Stepick-Biek, J S Remington
Affiliations

Detection of antigens in urine during acute toxoplasmosis

J Huskinson et al. J Clin Microbiol. 1989 May.

Abstract

Toxoplasma antigens were detected in sera and urine of mice acutely infected with Toxoplasma gondii. The concentrations of antigens in the urine samples measured by enzyme-linked immunosorbent assay were similar to those detected in the sera of the corresponding mice. The major antigens were not dialyzable and were largely destroyed by treatment with trichloroacetic acid and heat (100 degrees C for 1 h). Toxoplasma antigens were demonstrable on Western blots (immunoblots) of the urine samples.

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