Ultrasound-guided foam sclerotherapy of great saphenous vein with 2% polidocanol - one-year follow-up results
- PMID: 27458485
- PMCID: PMC4945613
- DOI: 10.5114/wiitm.2016.60579
Ultrasound-guided foam sclerotherapy of great saphenous vein with 2% polidocanol - one-year follow-up results
Abstract
Introduction: Ultrasound-guided foam sclerotherapy (UGFS) of varicose veins is a useful treatment option. It is a relatively safe method in the case of limited, small varicose veins. In theory, a justified concern could be raised that the injection of an active drug into the large superficial venous vessels may potentially cause life-threatening consequences.
Aim: To assess the safety and efficacy of UGFS using a 2% solution of polidocanol (Aethoxysklerol 2%) in the case of great saphenous vein incompetence.
Material and methods: Fifty-two patients with great saphenous vein incompetence underwent ultrasound-guided foam sclerotherapy. The efficacy criterion was the elimination of reflux measured ultrasonographically and withdrawal or decrease of complaints: 1 week, and 1, 3, 6 and 12 months after the treatment. Complications of sclerotherapy were reported during follow-up.
Results: Decrease or withdrawal of complaints of chronic venous insufficiency was reported in 96% of cases (50 patients). Disappearance or decrease of varicose veins was noted in all patients (100%). During examination after 12 months, full success of ultrasound was achieved in 38 (73%) cases, and 11 (21%) patients presented a partial desired effect according to the consensus from Tegernsee. Persistence of reflux longer than 1 s in the treated great saphenous vein was reported in 3 (6%) cases. Serious complications, such as deep vein thrombosis, pulmonary embolism, dyspnea, anaphylaxis, or neurological abnormalities, were not recorded.
Conclusions: Ultrasound-guided foam sclerotherapy of incompetent great saphenous vein and varicosities with 2% polidocanol was found to be an effective and safe method of treatment during 1 year of observation. However, longer observation is necessary.
Keywords: Doppler ultrasound; foam sclerotherapy; polidocanol; ultrasound-guided sclerotherapy; varicose veins.
Figures




Similar articles
-
Experience with concomitant ultrasound-guided foam sclerotherapy and endovenous laser treatment in chronic venous disorder and its influence on Health Related Quality of Life: interim analysis of more than 1000 consecutive procedures.Int Angiol. 2009 Aug;28(4):289-97. Int Angiol. 2009. PMID: 19648872
-
Efficacy and safety of great saphenous vein sclerotherapy using standardised polidocanol foam (ESAF): a randomised controlled multicentre clinical trial.Eur J Vasc Endovasc Surg. 2008 Feb;35(2):238-45. doi: 10.1016/j.ejvs.2007.09.006. Epub 2007 Nov 7. Eur J Vasc Endovasc Surg. 2008. PMID: 17988905 Clinical Trial.
-
Ultrasound-guided sclerotherapy of the great saphenous vein with 1% vs. 3% polidocanol foam: a multicentre double-blind randomised trial with 3-year follow-up.Eur J Vasc Endovasc Surg. 2010 Jun;39(6):779-86. doi: 10.1016/j.ejvs.2010.01.022. Epub 2010 Mar 4. Eur J Vasc Endovasc Surg. 2010. PMID: 20206556 Clinical Trial.
-
Which endovenous ablation method does offer a better long-term technical success in the treatment of the incompetent great saphenous vein? Review.Vascular. 2016 Dec;24(6):649-657. doi: 10.1177/1708538116648035. Epub 2016 Apr 28. Vascular. 2016. PMID: 27126643 Review.
-
Sclerotherapy and foam sclerotherapy for varicose veins.Phlebology. 2009 Dec;24(6):260-9. doi: 10.1258/phleb.2009.009050. Phlebology. 2009. PMID: 19952382 Review.
Cited by
-
Bilateral foam polidocanol sclerotherapy of great saphenous veins and their tributaries in synchronous procedure.J Vasc Bras. 2021 Jun 16;20:e20200178. doi: 10.1590/1677-5449.200178. J Vasc Bras. 2021. PMID: 34211536 Free PMC article.
-
EUS-guided lauromacrogol ablation with different concentrations of lauromacrogol for the treatment of pancreatic cystic neoplasm: A randomized controlled study.Endosc Ultrasound. 2025 Jan-Feb;14(1):4-12. doi: 10.1097/eus.0000000000000105. Epub 2025 Mar 3. Endosc Ultrasound. 2025. PMID: 40151595 Free PMC article.
References
-
- Robertson LA, Evans CJ, Lee AJ, et al. Incidence and risk factors for venous reflux in the general population: Edinburgh Vein Study. Eur J Vasc Endovasc Surg. 2014;48:208–14. - PubMed
-
- Perkins JM. Standard varicose vein surgery. Phlebology. 2009;24(Suppl 1):34–41. - PubMed
-
- Rasmussen LH, Lawaetz M, Bjoern L, et al. Randomized trial comparing endovenous laser ablation, radiofrequency ablation, foam sclerotherapy and surgical stripping for great saphenous varicose veins. Br J Surg. 2011;98:1079–87. - PubMed
-
- Orbach E. Sclerotherapy of varicose veins: utilisation of an intravenous air-block. Am J Surgery. 1944;66:362–6.
-
- Cabrera J, Cabrera J, Jr, García-Olmedo MA. Elargissement des limites de la sclerotherapie: Nouveaux produits sclerosants. Phlebologie. 1997;2:181–8.
LinkOut - more resources
Full Text Sources
Other Literature Sources