A Death Trap for Microglia
- PMID: 27459061
- DOI: 10.1016/j.devcel.2016.07.004
A Death Trap for Microglia
Abstract
Microglia, immune cells of the brain, originate from erythromyeloid precursors, far from the central nervous system. Xu et al. (2016) in this issue of Developmental Cell and Casano et al. (2016) recently in Cell Reports show that apoptotic neurons act as bait to "trap" microglia into colonizing the developing brain.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Microglia Colonization of Developing Zebrafish Midbrain Is Promoted by Apoptotic Neuron and Lysophosphatidylcholine.Dev Cell. 2016 Jul 25;38(2):214-22. doi: 10.1016/j.devcel.2016.06.018. Epub 2016 Jul 14. Dev Cell. 2016. PMID: 27424497
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Developmental Apoptosis Mediates Entry and Positioning of Microglia in the Zebrafish Brain.Cell Rep. 2016 Jul 26;16(4):897-906. doi: 10.1016/j.celrep.2016.06.033. Epub 2016 Jul 14. Cell Rep. 2016. PMID: 27425604
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