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. 2016 Jul 25;38(2):126-8.
doi: 10.1016/j.devcel.2016.07.006.

Microglia: Phagocytosing to Clear, Sculpt, and Eliminate

Soyon Hong  1 , Beth Stevens  2
Affiliations
Free article

Microglia: Phagocytosing to Clear, Sculpt, and Eliminate

Soyon Hong et al. Dev Cell. .
Free article

Abstract

Microglia are the primary phagocytes of the central nervous system. They eliminate excess functional connections between neurons to sculpt neuronal circuits during development and throughout adulthood. Understanding how microglia recognize and prune synapses during development is providing insight into synapse loss and dysfunction in disease.

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