Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Jul 26;134(4):265-6.
doi: 10.1161/CIRCULATIONAHA.116.022141.

Failing Heart and Starving Brain: Ketone Bodies to the Rescue

Heinrich Taegtmeyer  1
Affiliations

Failing Heart and Starving Brain: Ketone Bodies to the Rescue

Heinrich Taegtmeyer. Circulation. .
No abstract available

Keywords: cardiomyopathies; cardiovascular diseases; heart failure; ketone bodies; metabolism.

PubMed Disclaimer

Figures

Figure.
Figure.
The handwriting of Hans A. Krebs (“Main conclusion missing”) on the first draft of my DPhil thesis titled, “Metabolic Activities of the isolated Rat Heart” (Oxford, 1981).
See this image and copyright information in PMC

References

    1. Asimov I, Shulman JA, Isaac Asimov’s Book of Science and Nature Questions. New York: Weidenfeld & Nicholson, 1988: 281.
    1. Aubert G, Martin OJ, Horton JL, Lai L, Vega RB, Leone TC, Koves T, Gardell SJ, Krüger M, Hoppel CL, Lewandowski ED, Crawford PA, Muoio DM, Kelly DP. The failing heart relies on ketone bodies as a fuel. Circulation. 2016;133:698–705. doi: 10.1161/CIRCULATIONAHA.115.017355. - DOI - PMC - PubMed
    1. Bedi KC Jr, Snyder NW, Brandimarto J, Aziz M, Mesaros C, Worth AJ, Wang LL, Javaheri A, Blair IA, Margulies KB, Rame JE. Evidence for intramyocardial disruption of lipid metabolism and increased myocardial ketone utilization in advanced human heart failure. Circulation. 2016;133:706–716. doi: 10.1161/CIRCULATIONAHA.115.017545. - DOI - PMC - PubMed
    1. Taegtmeyer H, Hems R, Krebs HA. Utilization of energy-providing substrates in the isolated working rat heart. Biochem J. 1980;186:701–711. - PMC - PubMed
    1. Cahill GF Jr. Starvation in man. N Engl J Med. 1970;282:668–675. doi: 10.1056/NEJM197003192821209. - DOI - PubMed

Publication types