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Clinical Trial
. 2016 Jul 29;6(7):e448.
doi: 10.1038/bcj.2016.55.

Randomized phase III trial of consolidation therapy with bortezomib-lenalidomide-Dexamethasone (VRd) vs bortezomib-dexamethasone (Vd) for patients with multiple myeloma who have completed a dexamethasone based induction regimen

S J Jacobus  1 , S V Rajkumar  2 , M Weiss  3 , A K Stewart  4 , E A Stadtmauer  5 , N S Callander  6 , L M Dreosti  7 , M Q Lacy  2 , R Fonseca  4
Affiliations
Clinical Trial

Randomized phase III trial of consolidation therapy with bortezomib-lenalidomide-Dexamethasone (VRd) vs bortezomib-dexamethasone (Vd) for patients with multiple myeloma who have completed a dexamethasone based induction regimen

S J Jacobus et al. Blood Cancer J. .
No abstract available

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Conflict of interest statement

Dr Stadtmauer has been a consultant for Celgene, Takeda and Amgen. Dr Stewart has received honoraria for consulting from Celgene. Dr Dreosti has received speaker honorarium from Janssen Pharmaceuticals and congress sponsorship from Janssen Pharmaceuticals. Dr Fonseca has received consulting fees from Celgene and Takeda. The remaining authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Overall Survival by Treatment Arm.
See this image and copyright information in PMC

References

    1. Durie BG, Hoering A, Rajkumar SV, Abidi MH, Epstein J, Kahanic SP et al. Bortezomib, Lenalidomide and Dexamethasone vs. Lenalidomide and Dexamethasone in patients (Pts) with previously untreated multiple myeloma without an intent for immediate autologous stem cell transplant (ASCT). Results of the randomized phase III trial SWOG S0777. Blood (ASH Annual Meeting 177 Abstracts) 2015, 653. - PMC - PubMed
    1. National Comprehensive Cancer network (NCCN) Guidelines Version 4. Multiple Myeloma. 2015.
    1. Durie BG, Harousseay JL, Miquel JS, Blade J, Barlogie B, Anderson K et al. International uniform response criteria for multiple myeloma. Leukemia 2006; 20: 1467–1473. - PubMed
    1. Kaplan EL, Meier P. Nonparametric estimation from incomplete observation. J Am Stat Assoc 1958; 53: 457–481.
    1. Cox DR. Regression models and life tables. J Royal Stat Soc B 1972; 34: 181–220.

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