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Review
. 2016 Oct;57(10):1771-1777.
doi: 10.1194/jlr.R069575. Epub 2016 Jul 29.

The early years of lipoprotein research: from discovery to clinical application

Patty W Siri-Tarino  1 , Ronald M Krauss  2
Affiliations
Review

The early years of lipoprotein research: from discovery to clinical application

Patty W Siri-Tarino et al. J Lipid Res. 2016 Oct.

Abstract

This review outlines major milestones in the first four decades of lipoprotein research beginning with their discovery nearly 90 years ago. It focuses on the contributions of some of the key investigators during this era, and findings that set the stage for widespread clinical implementation of lipoprotein testing for evaluation and management of CVD risk.

Keywords: atherosclerosis; cholesterol; history; low density lipoprotein.

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Figures

Fig. 1.
Fig. 1.
John W. Gofman. Courtesy of the Lawrence Berkeley National Laboratory.
Fig. 2.
Fig. 2.
Frank Lindgren. Courtesy of the Lawrence Berkeley National Laboratory.
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Alexander V. Nichols (40).
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Richard J. Havel. Courtesy of the National Library of Medicine.
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Donald S. Fredrickson. Courtesy of the National Library of Medicine.
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Fig. 6.
Virgie and Bernard Shore. Courtesy of the Lawrence Berkeley National Laboratory.
See this image and copyright information in PMC

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