Cystic Fibrosis Papers of the Year 2015

Abstract

Studies published in the last year have expanded our knowledge of potential disease modifying agents in the treatment of class II, III and IV CFTR mutations, and included the first report of an efficacious gene therapy for CF. There is also an important message on increasing use of conventional chronic therapies even in milder disease, and the pernicious effect of chronic infection on pulmonary function.

Keywords: Cystic fibrosis; Gene therapy; Ivacaftor; Lumacaftor.