Absence of obvious link between supra-therapeutic serum levels of β lactams and clinical toxicity in ICU patients with acute renal failure treated with intermittent hemodialysis

Faten May^{1

2}, Najouah El-Helali³, Jean-François Timsit^{4

5

6}, Benoît Misset^{7

8}

Affiliations

¹ Medical Surgical ICU, Groupe Hospitalier Paris Saint Joseph, Service de Médecine Intensive et Réanimation, 185 rue Raymond Losserand, 75014, Paris, France. mayfaten68@gmail.com.
² Groupe hospitalier Paris Saint Joseph, Service de médecine intensive et réanimation, 185, rue Raymond Losserand, 75014, Paris, France. mayfaten68@gmail.com.
³ Clinical Microbiology Unit, Saint-Joseph Hospital Network, Paris, France.
⁴ Department of Biostatistics, Outcomerea, Paris, France.
⁵ Medical ICU, Bichat hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
⁶ Infection, Antimicrobials, Modelling, Evolution (IAME), UMR 1137, INSERM and Paris Diderot University, Department of Biostatistics - HUPNVS. - AP-HP, UFR de Médecine, Bichat University Hospital, Paris, France.
⁷ Medical Surgical ICU, Groupe Hospitalier Paris Saint Joseph, Service de Médecine Intensive et Réanimation, 185 rue Raymond Losserand, 75014, Paris, France.
⁸ Paris Descartes University, Paris, France.

Faten May et al. Crit Care. 2016.

. 2016 Aug 1;20(1):220.

doi: 10.1186/s13054-016-1394-2.

Faten May^{1

2}, Najouah El-Helali³, Jean-François Timsit^{4

5

6}, Benoît Misset^{7

8}

¹ Medical Surgical ICU, Groupe Hospitalier Paris Saint Joseph, Service de Médecine Intensive et Réanimation, 185 rue Raymond Losserand, 75014, Paris, France. mayfaten68@gmail.com.
² Groupe hospitalier Paris Saint Joseph, Service de médecine intensive et réanimation, 185, rue Raymond Losserand, 75014, Paris, France. mayfaten68@gmail.com.
³ Clinical Microbiology Unit, Saint-Joseph Hospital Network, Paris, France.
⁴ Department of Biostatistics, Outcomerea, Paris, France.
⁵ Medical ICU, Bichat hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
⁶ Infection, Antimicrobials, Modelling, Evolution (IAME), UMR 1137, INSERM and Paris Diderot University, Department of Biostatistics - HUPNVS. - AP-HP, UFR de Médecine, Bichat University Hospital, Paris, France.
⁷ Medical Surgical ICU, Groupe Hospitalier Paris Saint Joseph, Service de Médecine Intensive et Réanimation, 185 rue Raymond Losserand, 75014, Paris, France.
⁸ Paris Descartes University, Paris, France.

No abstract available

Comment in

Not all β-lactams are equal regarding neurotoxicity.
Chaïbi K, Chaussard M, Soussi S, Lafaurie M, Legrand M. Chaïbi K, et al. Crit Care. 2016 Oct 27;20(1):350. doi: 10.1186/s13054-016-1522-z. Crit Care. 2016. PMID: 27784324 Free PMC article. No abstract available.

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