Filling the (SR)GAP in Excitatory/Inhibitory Balance
- PMID: 27477010
- DOI: 10.1016/j.neuron.2016.07.008
Filling the (SR)GAP in Excitatory/Inhibitory Balance
Abstract
In this issue of Neuron, Fossati et al. (2016) report that through its domain structure, SRGAP2A, a Rho-GTPase-activating protein, can co-regulate excitatory and inhibitory synapse development, offering a putative evolutionary genetic mechanism for preserving excitatory/inhibitory balance during speciation.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses.Neuron. 2016 Jul 20;91(2):356-69. doi: 10.1016/j.neuron.2016.06.013. Epub 2016 Jun 30. Neuron. 2016. PMID: 27373832 Free PMC article.
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