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. 2016 Jul 1;124(7):A124-9.
doi: 10.1289/ehp.124-A124.

Lasting Impact of an Ephemeral Organ: The Role of the Placenta in Fetal Programming

Lindsey Konkel

Lasting Impact of an Ephemeral Organ: The Role of the Placenta in Fetal Programming

Lindsey Konkel. Environ Health Perspect. .
No abstract available

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Figures

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Recent advances in molecular and imaging technologies, “omics” fields, and data sciences are offering researchers an unprecedented look at the placenta, the master regulator of the fetal environment. © EPA/National Geographic Channel/Alamy
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Studies of infants conceived during the Dutch “Hunger Winter” provided some of the earliest clues that prenatal stress could affect health much later in life. © Nationaal Archief
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Placental Development
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In one study, the placental microbiome had a similar taxonomic profile as the oral microbiome, illustrated here by Bray-Curtis (B-C) dissimilarity. B-C dissimilarity reflects the extent to which two sites have dissimilar compositions, with 0 indicating total similarity and 1 indicating total dissimilarity—the thicker the connecting line, the greater the similarity of the taxonomic profile. Source: Aagard et al. (2014)
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References

    1. Roseboom TJ, et al. Effects of prenatal exposure to the Dutch famine on adult disease in later life: an overview. Mol Cell Endocrinol 185 1–2 93 98 2001, doi:10.1016/S0303-7207(01)00721-3 - DOI - PubMed
    1. Wadhwa PD, et al. Developmental origins of health and disease: brief history of the approach and current focus on epigenetic mechanisms. Semin Reprod Med 27 5 358 368 2009, doi:10.1055/s-0029-1237424 - DOI - PMC - PubMed
    1. Barker DJP, et al. Fetal origins of adult disease: strength of effects and biological basis. Int J Epidemiol 31 6 1235 1239 2002, doi:10.1093/ije/31.6.1235 - DOI - PubMed
    1. Grandjean P, et al. Life-long implications of developmental exposure and environmental stressors: new perspectives. Endocrinology 156 10 3408 3415 2015, doi:10.1210/EN.2015-1350 - DOI - PMC - PubMed
    1. Long EC. The placenta in lore and legend. Bull Med Libr Assoc 51 2 233 241 1963, PMID: - PMC - PubMed

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