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Multicenter Study
. 2016 Sep 23;60(10):6393-7.
doi: 10.1128/AAC.01125-16. Print 2016 Oct.

In Vitro Evaluation of the Activity of Imipenem-Relebactam against 451 Recent Clinical Isolates of Bacteroides Group and Related Species

David R Snydman  1 , Nilda V Jacobus  2 , Laura A McDermott  2
Affiliations
Multicenter Study

In Vitro Evaluation of the Activity of Imipenem-Relebactam against 451 Recent Clinical Isolates of Bacteroides Group and Related Species

David R Snydman et al. Antimicrob Agents Chemother. .

Abstract

We evaluated the in vitro activity of imipenem-relebactam (imipenem-MK7655) against 451 recent clinical isolates within the Bacteroides group and related species. Relebactam did not enhance or inhibit the activity of imipenem against Bacteroides fragilis or other Bacteroides species. No synergistic or antagonistic effect was observed. The MICs of imipenem-relebactam were equal to or within one dilution of the MICs of these isolates to imipenem.

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