Ultrafast Magnetic Resonance Imaging for Iron Quantification in Thalassemia Participants in the Developing World: The TIC-TOC Study (Thailand and UK International Collaboration in Thalassaemia Optimising Ultrafast CMR)

Amna Abdel-Gadir¹, Yongkasem Vorasettakarnkij², Hataichanok Ngamkasem², Sabrina Nordin², Emmanuel A Ako², Monravee Tumkosit², Pranee Sucharitchan², Noppacharn Uaprasert², Peter Kellman², Stefan K Piechnik², Marianna Fontana², Juliano L Fernandes², Charlotte Manisty², Mark Westwood², John B Porter², J Malcolm Walker², James C Moon²

Affiliations

¹ From Institute of Cardiovascular Science, University College London, UK (A.A.-G., S.N., E.A.A., M.F., C.M., J.M.W., J.C.M.);Barts Heart Centre, London, UK (A.A.-G., S.N., E.A.A., C.M., M.W., J.C.M.); Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand (Y.V., M.T., P.S., N.U.); King Chulalongkorn Memorial Hospital, Bangkok, Thailand (Y.V., M.T., P.S., N.U.); Queen Savang Vadhana Memorial Hospital, Sriracha, Thailand (H.N.); Medical Signal and Image Processing Program, National Heart, Lung, and Blood Institute, Bethesda, MD (P.K.); University of Oxford Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, UK (S.K.P.); National Amyloidosis Centre, Royal Free Hospital, London, UK (M.F.); Cardiovascular Imaging Center, Jose Michel Kalaf Research Institute, Sao Paulo, Brazil (J.L.F.); Haematology Department, University College London Hospitals, UK (J.B.P.); and Hatter Cardiovascular Institute, University College Hospital, London, UK (J.M.W.). a.abdel-gadir@ucl.ac.uk.
² From Institute of Cardiovascular Science, University College London, UK (A.A.-G., S.N., E.A.A., M.F., C.M., J.M.W., J.C.M.);Barts Heart Centre, London, UK (A.A.-G., S.N., E.A.A., C.M., M.W., J.C.M.); Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand (Y.V., M.T., P.S., N.U.); King Chulalongkorn Memorial Hospital, Bangkok, Thailand (Y.V., M.T., P.S., N.U.); Queen Savang Vadhana Memorial Hospital, Sriracha, Thailand (H.N.); Medical Signal and Image Processing Program, National Heart, Lung, and Blood Institute, Bethesda, MD (P.K.); University of Oxford Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, UK (S.K.P.); National Amyloidosis Centre, Royal Free Hospital, London, UK (M.F.); Cardiovascular Imaging Center, Jose Michel Kalaf Research Institute, Sao Paulo, Brazil (J.L.F.); Haematology Department, University College London Hospitals, UK (J.B.P.); and Hatter Cardiovascular Institute, University College Hospital, London, UK (J.M.W.).

PMID: 27482005
PMCID: PMC4966915
DOI: 10.1161/CIRCULATIONAHA.116.022803

Ultrafast Magnetic Resonance Imaging for Iron Quantification in Thalassemia Participants in the Developing World: The TIC-TOC Study (Thailand and UK International Collaboration in Thalassaemia Optimising Ultrafast CMR)

Amna Abdel-Gadir et al. Circulation. 2016.

. 2016 Aug 2;134(5):432-4.

doi: 10.1161/CIRCULATIONAHA.116.022803.

Authors

Affiliations

¹ From Institute of Cardiovascular Science, University College London, UK (A.A.-G., S.N., E.A.A., M.F., C.M., J.M.W., J.C.M.);Barts Heart Centre, London, UK (A.A.-G., S.N., E.A.A., C.M., M.W., J.C.M.); Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand (Y.V., M.T., P.S., N.U.); King Chulalongkorn Memorial Hospital, Bangkok, Thailand (Y.V., M.T., P.S., N.U.); Queen Savang Vadhana Memorial Hospital, Sriracha, Thailand (H.N.); Medical Signal and Image Processing Program, National Heart, Lung, and Blood Institute, Bethesda, MD (P.K.); University of Oxford Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, UK (S.K.P.); National Amyloidosis Centre, Royal Free Hospital, London, UK (M.F.); Cardiovascular Imaging Center, Jose Michel Kalaf Research Institute, Sao Paulo, Brazil (J.L.F.); Haematology Department, University College London Hospitals, UK (J.B.P.); and Hatter Cardiovascular Institute, University College Hospital, London, UK (J.M.W.). a.abdel-gadir@ucl.ac.uk.
² From Institute of Cardiovascular Science, University College London, UK (A.A.-G., S.N., E.A.A., M.F., C.M., J.M.W., J.C.M.);Barts Heart Centre, London, UK (A.A.-G., S.N., E.A.A., C.M., M.W., J.C.M.); Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand (Y.V., M.T., P.S., N.U.); King Chulalongkorn Memorial Hospital, Bangkok, Thailand (Y.V., M.T., P.S., N.U.); Queen Savang Vadhana Memorial Hospital, Sriracha, Thailand (H.N.); Medical Signal and Image Processing Program, National Heart, Lung, and Blood Institute, Bethesda, MD (P.K.); University of Oxford Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, Division of Cardiovascular Medicine, UK (S.K.P.); National Amyloidosis Centre, Royal Free Hospital, London, UK (M.F.); Cardiovascular Imaging Center, Jose Michel Kalaf Research Institute, Sao Paulo, Brazil (J.L.F.); Haematology Department, University College London Hospitals, UK (J.B.P.); and Hatter Cardiovascular Institute, University College Hospital, London, UK (J.M.W.).

PMID: 27482005
PMCID: PMC4966915
DOI: 10.1161/CIRCULATIONAHA.116.022803

No abstract available

Keywords: cardiomyopathies; diagnosis; iron overload; magnetic resonance imaging.

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References

1. Higgs DR, Engel JD, Stamatoyannopoulos G. Thalassaemia. Lancet. 2012;379:373–383. doi: 10.1016/S0140-6736(11)60283-3. - PubMed
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1. Carpenter JP, He T, Kirk P, Roughton M, Anderson LJ, de Noronha SV, Sheppard MN, Porter JB, Walker JM, Wood JC, Galanello R, Forni G, Catani G, Matta G, Fucharoen S, Fleming A, House MJ, Black G, Firmin DN, St Pierre TG, Pennell DJ. On T2* magnetic resonance and cardiac iron. Circulation. 2011;123:1519–1528. doi: 10.1161/CIRCULATIONAHA.110.007641. - PMC - PubMed
1. Captur G, Gatehouse P, Kellman P, Heslinga FG, Keenan K, Bruehl R, Prothmann M, Graves MJ, Chiribiri A, Ittermann B, Pang W, Nezafat R, Salerno M, Moon JC. A T1 and ECV phantom for global T1 mapping quality assurance: the T1 Mapping and ECV Standardisation in CMR (T1MES) program. J Cardiovasc Magn Reson. 2016;18:1–3. - PMC - PubMed

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Ultrafast Magnetic Resonance Imaging for Iron Quantification in Thalassemia Participants in the Developing World: The TIC-TOC Study (Thailand and UK International Collaboration in Thalassaemia Optimising Ultrafast CMR)

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Ultrafast Magnetic Resonance Imaging for Iron Quantification in Thalassemia Participants in the Developing World: The TIC-TOC Study (Thailand and UK International Collaboration in Thalassaemia Optimising Ultrafast CMR)

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