Fatal aluminium phosphide poisoning
- PMID: 27486362
- PMCID: PMC4961899
- DOI: 10.1515/intox-2015-0010
Fatal aluminium phosphide poisoning
Abstract
Aluminium phosphide (AlP) is a cheap solid fumigant and a highly toxic pesticide which is commonly used for grain preservation. AlP has currently aroused interest with a rising number of cases in the past four decades due to increased use for agricultural and non-agricultural purposes. Its easy availability in the markets has increased also its misuse for committing suicide. Phosphine inhibits cellular oxygen utilization and can induce lipid peroxidation. Poisoning with AlP has often occurred in attempts to commit suicide, and that more often in adults than in teenagers. This is a case of suicidal consumption of aluminium phosphide by a 32-year-old young medical anesthetist. Toxicological analyses detected aluminium phosphide. We believe that free access of celphos tablets in grain markets should be prohibited by law.
Keywords: aluminium phosphide; phosphine; poisoning; suicide.
Figures
References
-
- Arora B, Punia RS, Kalra R, Chugh SN, Arora DR. Histopathological changes in aluminium phosphide poisoning. J Indian Med Assoc. 1995;93(10):380–381. - PubMed
-
- Jain AK, Nigam M, Garg SD, Dubey BP, Arora A. Aluminium phosphide poisoning – Autopsy findings. JIAFM. 2005;27(1):35–39.
-
- Bolter C, Chefurka W. Extra mitochondrial release of hydrogen peroxide from insects and mouse liver mitochondria using respiratory inhibitors--phosphine, nyxothiazol, antimycin and spectral analysis of inhibited cytochromes. Arch Biochem Biophys. 1989;278(1):65–72. - PubMed
-
- Chefurka W, Kashi KP, Bond EJ. The effect of phosphine on electron transport in mitochondria. Pest Biochem Physiol. 1976;6:350–362.
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous