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. 2016 Oct;45(10):845-855.
doi: 10.1016/j.lpm.2016.07.001. Epub 2016 Aug 1.

[Cardiac amyloidosis: How to recognize them and manage them?]

[Article in French]
Diane Bodez  1 , Arnault Galat  2 , Aziz Guellich  2 , Jean-François Deux  3 , Jean Rosso  4 , Fabien Le Bras  5 , Benoît Funalot  6 , Pascale Fanen  6 , Nicole Benhaiem  7 , Violaine Planté-Bordeneuve  8 , Jean-Luc Dubois-Randé  9 , Nicolas Lellouche  2 , Soulef Guendouz  2 , Valérie Molinier-Frenkel  10 , Dania Mohty  11 , Thibaud Damy  2
Affiliations

[Cardiac amyloidosis: How to recognize them and manage them?]

[Article in French]
Diane Bodez et al. Presse Med. 2016 Oct.

Abstract

Cardiac amyloidosis must be suspected in all cases of hypertrophic cardiomyopathy with preserved left ventricular ejection fraction to allow specific management. Final diagnosis needs pathological evidence, but bone scintigraphy may be an alternative for TTR amyloidosis. Invasive samplings are limited by new tools. Amyloidosis typing is required to start specific therapies if possible. Main specific treatments that are available are chemotherapy for AL; transthyretin stabilizer or gene therapy, studied for TTR-related cardiac amyloidosis.

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