Attaching Accessory Devices to the Replisome
- PMID: 27494554
- DOI: 10.1016/j.molcel.2016.07.017
Attaching Accessory Devices to the Replisome
Abstract
Evidence mounts, via two studies published in Molecular Cell (Villa et al. 2016; Samora et al. 2016), that Ctf4 recruits to the replisome various factors that play diverse roles in chromosome duplication, by acting as an interaction hub.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.Mol Cell. 2016 Aug 4;63(3):385-96. doi: 10.1016/j.molcel.2016.06.009. Epub 2016 Jul 7. Mol Cell. 2016. PMID: 27397685 Free PMC article.
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Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome.Mol Cell. 2016 Aug 4;63(3):371-84. doi: 10.1016/j.molcel.2016.05.036. Epub 2016 Jul 7. Mol Cell. 2016. PMID: 27397686 Free PMC article.
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