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. 2016 Aug 4;19(2):145-146.
doi: 10.1016/j.stem.2016.07.017.

Neural Differentiation in the Third Dimension: Generating a Human Midbrain

Rebecca M Marton  1 , Sergiu P Paşca  2
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Neural Differentiation in the Third Dimension: Generating a Human Midbrain

Rebecca M Marton et al. Cell Stem Cell. .
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Abstract

In recent years, technological improvements in three-dimensional (3D) culture systems have enabled the generation of organoids or spheroids representing a variety of tissues, including the brain. In this issue of Cell Stem Cell, Jo et al. (2016) describe a 3D culture model of the human midbrain containing dopaminergic neurons and neuromelanin.

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