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Review
. 2016 Oct:86:92-99.
doi: 10.1016/j.cyto.2016.07.015. Epub 2016 Aug 3.

Anti cytokine therapy in chronic inflammatory arthritis

Charlotte Thompson  1 , Ruth Davies  2 , Ernest Choy  3
Affiliations
Review

Anti cytokine therapy in chronic inflammatory arthritis

Charlotte Thompson et al. Cytokine. 2016 Oct.

Abstract

This is a review looking at anti cytokine therapy in Rheumatoid Arthritis (RA), Psoriatic Arthritis (PSA) and Ankylosing Spondylitis (AS). The review explores the similarities and differences in the clinical features, as well as treatments and cytokines involved in the development and propagation of the disease. Particular attention is paid to TNFα inhibitors IL-1ra, IL-6 and JAK kinase Inhibitors, anti IL23 and IL-12 and the new developments with anti-IL-17.

Keywords: Ankylosing Spondylitis; Cytokine; IL27; Inflammatory arthritis; Psoriatic Arthritis; Rheumatoid Arthritis; TNFα inhibitor.

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