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Case Reports
. 2016 Jun;10(6):DD06-8.
doi: 10.7860/JCDR/2016/18666.7990. Epub 2016 Jun 1.

Biofilm in Osteomyelitis caused by a Rare Pathogen, Morganella morganii : A Case Report

Asmita De  1 , Hirak Jyoti Raj  2 , Prasanta Kumar Maiti  3
Affiliations
Case Reports

Biofilm in Osteomyelitis caused by a Rare Pathogen, Morganella morganii : A Case Report

Asmita De et al. J Clin Diagn Res. 2016 Jun.

Abstract

Morganella morganii is a member of Enterobacteriaceae family, whose natural habitat is the human gastrointestinal tract. It rarely causes infection alone and is generally encountered in immunosuppressed patients. Osteoarticular pathologies are not commonly observed with Morganella morganii and infections by it have high mortality rate. Biofilm colonization is a causative factor behind the chronicity and/or refractoriness of certain infections. Biofilms colonize on inert medical devices, prosthesis, fibrosed tissues, sinus tracts as well as dead bones as in case of chronic osteomyelitis. Morganella morganii is not a common pathogen to produce biofilm. In this case report, we present a 56-year-old male patient with chronic osteomyelitis of right proximal tibia caused by biofilm producing strain of Morganella morganii, following trauma.

Keywords: Chronic osteomyelitis; Immunosuppression; Osteoarticular.

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Figures

[Table/Fig-1]:
[Table/Fig-1]:
Lesion of osteomyelitis below right knee.
[Table/Fig-2]:
[Table/Fig-2]:
Biochemical tests for identification.
[Table/Fig-3]:
[Table/Fig-3]:
Microtitre plate method for detection of biofilm by Stepanovic et al., Row G (G1, G2, G3, G4) indicators of biofilm production by Morganella morganii.
See this image and copyright information in PMC

References

    1. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; Twenty-fourth Informational Supplement. Pennsylvania, Wayne, USA, 2014.
    1. Stepanovic S, Vukovic D, Dakic I, Savic B, Svabic-Vlahovic M. A modified microtiter-plate test for quantification of staphylococcal biofilm formation. J Microbiol Methods. 2000;40(2):175–79. - PubMed
    1. Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J. Harrison’s principles of internal medicine. 19th ed. New York: Mc Graw Hill Medical; 2015. pp. 838–45.
    1. Costerton JW, Stewart PS, Greenberg EP. Bacterial biofilms: A common cause of persistent infections. Science. 1999;284(5418):1318–22. - PubMed
    1. Koyuncu W, Ozan F. Morganella morganii osteomyelitis complicated by secondary septic knee arthritis: a case report. Acta Orthop Traumatol Turc. 2012;46(6):464–67. - PubMed

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