Benign Fibrous Histiocytoma of Mandible: A Case Report and Updated Review

Abstract

Benign Fibrous Histiocytoma (BFH) is a well recognised tumour of the soft tissue, developing entirely within the subcutaneous tissue, the deep soft tissues or in the parenchymal organs. However, BFH of bones is poorly defined. It has been rarely reported in the bones with femur, tibia and pelvic bone being the most commonly affected bones. Involvement of the jawbones is rare. Their clinical and radiographic features often simulate the common odontogenic and non-odontogenic lesions of the jaws. Hence, it is imperative for a dentist to have proper knowledge of various conditions affecting the jaws. Here we report a case of BFH which presented as an indolent swelling of the right mandibular posterior region for 15 years. The case emphasizes the need for considering BFH in the differential diagnosis of swellings of the jaws.

Keywords: Fibroblasic; Histiocytic; Swelling.

[Table/Fig-1]:

Extra oral photograph of the patient showing mild asymmetry of right lower face.

[Table/Fig-2]:

Intra oral view.

[Table/Fig-3]:

Panoramic radiograph showing mixed radio opaque radiolucent lesion with ill defined borders.

[Table/Fig-4]:

Postero-anterior view showing mixed radio opaque radiolucent lesion.

[Table/Fig-5]:

Occlusal radiograph showing buccal and lingual cortical plate expansion.

[Table/Fig-6]:

CT axial view showing expansile lesion.

[Table/Fig-7]:

CT coronal view.

[Table/Fig-8]:

H & E stained section at 100x magnification showing storiform pattern arrangement of spindle shaped cells.

[Table/Fig-9]:

H & E stained section showing sheets of foamy histiocytes and areas of haemorrhage 100x.

[Table/Fig-10]:

H&E stained section at 400x magnification, giant cell seen.

[Table/Fig-11]:

Tumour cells diffusely positive for vimentin.

[Table/Fig-12]:

Tumour cells focally positive for CD 68.

[Table/Fig-13]:

Intra operative view.

[Table/Fig-14]:

Post operative view.